ENROLLING CLINICAL TRIALS

If you are interested in participating in a clinical trial or want to learn more about current studies at Clinvest/Headache Care Center, contact us for more information. If you would like to be notified of new studies, click to email our staff or call 417.883.7889.

Enrolling StudyMigraines 4-14 Month more info Enrolling StudyCongestive Heart Failure more info Enrolling StudyMigraine Treatment not Working?more info
Enrolling StudyPain Medication Side Effects more info Enrolling StudyCOPD more info Enrolling StudyChronic Headache-Head Injury more info
Enrolling StudyBotox® for Migraine more info Enrolling StudyMore Frequent Migraines Full Enrolling StudyMenstrual Headaches Full
Enrolling StudyRheumatoid Arthritis more info Enrolling StudyChronic Headaches more info Enrolling StudyTeen Migraine more info
Enrolling StudyHeart Attack more info Enrolling Study2-8 Migraines a Month more info Enrolling StudyDiabetic Peripheral Neuropathy more info

 

New Drug Category Being Tested for Diabetic Peripheral Neuropathy

 
Rheumatoid Arthritis  


Diabetic Peripheral Neuropathy, also known as DPN, can have significant impact on the lives
Type I or II diabetics who suffer from this painful condition.
We are looking for individuals for a medical research study who:

  • Suffer from Type I or II diabetes
  • Have experienced moderate to severe pain associated with DPN for at least 6 months
  • Are between the ages of 18-65

The purpose of the study is to determine the safety and effectiveness of an investigational drug, in a new drug category, for people with DPN.  If you qualify and choose to participate you will receive all study-related medical evaluations and study drug or placebo (an inactive look a- like substance) at no charge. Compensation for time and travel is also provided. 

For more information please call 417.883.7889

Email Contact.

 

 

Does Your Monthly Routine Involve Dealing With 4-14 Migraine Headaches?

 
Rheumatoid Arthritis  

People who experience that many headaches each month may be among those whose treatment for migraine prevention isn't effective. They also could be among the 75
% of migraine sufferers who aren't taking drugs for migraine prevention but might benefit.

Please consider enrolling in this research study testing a new class of drugs in development for migraine prevention if you:

  • Are age 18-64
  • Have experienced a headache on 4-14 days during the past 3 months
  • Are willing to help find a way to prevent frequent headaches from becoming a chronic disorder

Qualified candidates will receive study related medical evaluations and investigational drug at no charge. Compensation for time and travel is also provided. 

For more information, please contact Clinvest at 417.883.7889. Email Contact.

 

 

Do You Suffer from the Side Effects of Daily Pain Medication?

 
Rheumatoid Arthritis  

Constipation is a common problem for those who must rely on narcotics to manage chronic pain. If you suffer from this unpleasant and uncomfortable side effect, you may be interested in participating in a medical research study testing an investigational drug used to treat opioid induced constipation.

In order to qualify you must:

  • Suffer from constipation related to the use of narcotic pain medications
  • Have a condition that, for at least the last 3 months, has required daily use of narcotic pain
    medication.

If you meet enrollment criteria and choose to participate in this 6 week study you will receive all study-related medical evaluations and study drug at no charge. Compensation for travel is also provided.
For more information call Clinvest at 417.883.7889. Email Contact.

 

 

Botox® for Migraine Prevention

 
Rheumatoid Arthritis  

Clinvest is currently recruiting volunteers to participate in a two year medical research study to see if Botox® reduces the number and severity of chronic migraine headaches.
 
Please consider enrolling in this medical research study if you:

  • Are 18 years of age or older  
  • Experience a headache on 15 or more days each month
  • Are willing to help find a way to manage chronic headaches

Qualified candidates will receive study related medical evaluations and investigational drug at no charge. For more information, please contact Clinvest at 417.883.7889. Email Contact.

 

 

IS YOUR CURRENT MIGRAINE TREATMENT NOT QUITE DOING THE JOB?

 
Rheumatoid Arthritis  

Do you know that when you have a migraine your gastrointestinal system slows down?  That might not seem like such a big deal unless you are looking for fast relief of your migraine. The longer it takes your body to absorb medications the longer it may take you to experience the relief you’re looking for. We are currently conducting a medical research study to test a powdered form of an FDA approved migraine drug administered by a nasal delivery device. The purpose of the study is to evaluate the time it takes for users to experience headache relief. Won’t you consider joining this research study if you:

  • Are a male or female between the ages of 18-65
  • Experience an average of 1-8 migraines a month

Qualified candidates will receive study related medical evaluations and investigational drug or placebo at no cost. Compensation for time and travel is also provided.

For more information contact 417.883.7889 Email Contact.

 

 

Do you suffer from severe to very severe Chronic Obstructive Pulmonary Disease?

 
Rheumatoid Arthritis  

A nation- wide research study is underway to test a drug approved by the FDA for the treatment of COPD. The purpose of the study is to see if the drug safely and effectively helps reduce the number of COPD exacerbations/flare ups when added to treatment with Advair or Symbicort.
Please consider participating if you:

• Are age 40 or older, male or female
• Have a smoking history of at least 20 pack years
• Do not require the use of supplemental oxygen or use 15 hours or less/day

Call to see if you qualify for this medical research study. No insurance is necessary because if you qualify and choose to participate you will receive all study related medical evaluations and study drug at no charge. Compensation for time and travel is also provided. This study is being conducted by Clinvest in cooperation with Dr. Robert Powers at Ozarks Community Hospital. For more information call 417 883-7889. Email Contact.

 

 

People Who Suffer from Rheumatoid Arthritis Wanted for Nationwide Research Study

 
Rheumatoid Arthritis  

If you suffer from rheumatoid arthritis you are probably aware that the currently available treatments only partially control the disease. Scientists are working to develop new drugs that more effectively reduce inflammation and preserve bone and cartilage. If you suffer from rheumatoid arthritis and:

  • Are age 18 or older
  • Have NOT taken a disease modifying treatment (DMT) such as MTX, leflunamide or sulfasalazine OR have been taking a DMT at a stable dose for at least 3 months.

If you qualify and choose to participate in this study you receive all study-related medical evaluations and monitoring by medical professionals and study drug at no cost. Compensation for time and travel is also provided. Clinvest is conducting this study in cooperation with rheumatologist, Dr. Anne Winkler.

For more information please contact Clinvest 417.883.7889 or Email Contact.

 

 

People Who Have Experienced a Heart Attack Wanted for Nationwide Research Study Back to Top

 
Rheumatoid Arthritis  

Scientists now understand that chronic inflammation is a key factor in the development of blockages in the arteries leading to heart attacks. An investigational drug, administered by injection every 3 months, is being studied to see if it safely and effectively reduces inflammation. If you suffered a heart attack more than 30 days ago and:

  • Are age 18 or older
  • Have no current plans to have heart bypass surgery, angioplasty or placement of a stent
  • Have not had heart bypass surgery in the past 3 years

Please consider enrolling in this study. If you qualify and choose to participate in this medical research study you receive all study-related medical evaluations and monitoring by medical professionals and study drug at no cost. Compensation for time and travel is also provided.

Clinvest is conducting this study in cooperation with cardiologist, Dr. John Best, at Citizen's Memorial Hospital in Bolivar, MO.

For more information please contact Clinvest at 417.883.7889 or Email Link.

 

 

People With Congestive Heart Failure Wanted for Nationwide Research Study Back to Top

 
Rheumatoid Arthritis  

Congestive heart failure is a health problem that is becoming increasingly more common. People who suffer from CHF often experience poor quality of life and frequent hospitalizations. This study will test an investigational drug to see if it delays events such as hospitalization related to CHF. Candidates must be:

  • Age 18 or older
  • Currently taking medications classified as AECIs or ARBC which are commonly used to treat CHF

If you qualify and choose to participate in this medical research study you receive all study-related medical evaluations and monitoring by research professionals and study drug at no cost. Compensation for time and travel is also provided.

Clinvest is conducting this study in cooperation with Dr. John Best at Citizen's Memorial Hospital in Bolivar.For more information please contact Clinvest at 417.883.7889 or Email Link.

 

 

Are Your Migraines Occurring More Frequently? Back to Top

 
Rheumatoid Arthritis  

Clinvest is currently recruiting volunteers to participate in a medical research study to see if a drug that is investigational for frequent migraine plus migraine education reduces the number and severity of these headaches. If you:

  • Are age 18-65
  • Have experienced a headache on 6-14 days during the past 3 months
  • Are willing to help find a way to prevent frequent headaches from becoming a chronic disorder

Qualified candidates will receive study related medical evaluations, investigational drug and migraine education at no charge. Compensation for time and travel is also provided.

For more information please contact Clinvest at 417.883.7889 or Email Link.

 

 

Do You Suffer from Chronic Headaches? Back to Top

 
Rheumatoid Arthritis  

Clinvest is currently recruiting volunteers to participate in a medical research study to see if an investigational drug reduces the number and severity of chronic headaches.
Please consider enrolling in this medical research study if you:

  • Are age 18-65
  • Experience a headache on 15 or more days each month
  • Are willing to help find a way to manage chronic headaches

Qualified candidates will receive study related medical evaluations and investigational drug at no charge. Compensation for time and travel is also provided. For more information please contact Clinvest at 417.883.7889 or Email Link.

 

 

Have you had a mild head injury that has left you with chronic headaches? Back to Top

 
Rheumatoid Arthritis  

Clinvest is conducting a medical research study testing an approved migraine drug to see if it safely and effectively relieves post traumatic headaches. Please consider enrolling in this medical research study if you:

  • Are between the ages of 18 and 65
  • Have had a problem with headaches since the injury
  • Have trouble with concentration and memory due to the headaches

No insurance is necessary because if you qualify and choose to participate you will receive all study related medical evaluations and study drug at no charge. Compensation for time and travel is also provided. For more information please contact Clinvest at 417.883.7889 or Email Contact.

 

 

Menstrual Headaches Back to Top

 
Rheumatoid Arthritis  

Clinvest is currently recruiting women to participate in a medical research study testing a migraine drug for the treatment of menstrually associated headaches.
Please consider volunteering for this study if you:

  • Are age 18 or older
  • Have regular cycles
  • Have experienced a headache during 2 of your last 3 monthly cycles

No insurance is necessary because if you qualify and choose to participate you will receive all study related medical evaluations and study drug. Compensation for time and travel is also provided.

For more information please contact Clinvest at 417.883.7889 or Email Contact.

 

 

Are Migraines Disrupting Your Teens Life? Back to Top

 
Rheumatoid Arthritis  

Like adults, kids have migraines. Unfortunately these headaches are often undertreated.
Please consider enrolling in this medical research study if you:

  • Is between the ages of 12 and 17
  • Experiences 15 or fewer days of headache each month
  • Is willing to help find treatment for adolescent migraine

The purpose of the study is to test a medication already approved for adult migraine but is investigational in individuals under age 18. Study participants will receive study related medical evaluations, and study medicine at no cost to you. Compensation for time and travel is also provided.

Call 417.883.7889 for more information about your child's possible participation in this trial or Email Contact.

 

 

Do You Experience Average of 2-8 Migraines a Month?

 
Rheumatoid Arthritis  

If the answer is yes, please consider volunteering for a medical research study comparing the safety and effectiveness of an investigational drug to sumatriptan or placebo, an inactive substance.

You may qualify if:

• Are between the ages of 18 and 65
• Suffered from migraines for at least a year
• Are in overall good health

Call to learn more about this medical research study. Qualified candidates will receive study related exams, study drug, plus compensation for time and travel.

For more information call 417-883-7889. Email Contact.

 

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