Current Studies Study Topics
 

If you are interested in participating in a clinical study or want to learn more about current studies at Clinvest/Headache Care Center, contact us for more information. If you would like to be notified of new studies, click here to email our staff.

People Who Suffer from Rheumatoid Arthritis Wanted for Nationwide Research Study

If you suffer from rheumatoid arthritis you are probably aware that the currently available treatments only partially control the disease.  Scientists are working to develop new drugs that more effectively reduce inflammation and preserve bone and cartilage.

If you suffer from rheumatoid arthritis and:

  • Are age 18 or older
  • Have NOT taken a disease modifying treatment (DMT) such as MTX, leflunamide or sulfasalazine OR have been taking a DMT at a stable dose for at least 3 months

Please consider enrolling in this medical research study. If you qualify and choose to participate in this study you receive all study-related medical evaluations and monitoring by medical professionals and study drug at no cost. Compensation for time and travel is also provided. Clinvest is conducting this study in cooperation with rheumatologist, Dr. Anne Winkler.

For more information please contact Clinvest 417-883-7889 or Email Contact.

 

Menstrual Headaches

Clinvest is currently recruiting women to participate in a medical research study
testing a migraine drug for the treatment of menstrually associated headaches.

If you:

  • Are age 18 or older
  • Have regular cycles
  • Have experienced a headache during 2 of your last 3 monthly cycles

Please consider volunteering for this study.  No insurance is necessary because if you qualify and choose to participate you will receive all study related medical evaluations and study drug. Compensation for time and travel is also provided. 

For more information, please call 417-883-7889.

Email Contact

People Who Have Experienced a Heart Attack Wanted for
Nationwide Research Study

Scientists now understand that chronic inflammation is a key factor in the development of blockages in the arteries leading to heart attacks. An investigational drug, administered by injection every 3 months, is being studied to see if it safely and effectively reduces inflammation.

If you suffered a heart attack more than 30 days ago and:

  • Are age 18 or older
  • Have no current plans to have heart bypass surgery, angioplasty or placement of a stent
  • Have not had heart bypass surgery in the past 3 years

Please consider enrolling in this study. If you qualify and choose to participate in this medical research study you receive all study-related medical evaluations and monitoring by medical professionals and study drug at no cost. Compensation for time and travel is also provided.

Clinvest is conducting this study in cooperation with cardiologist, Dr. John Best, at Citizen’s Memorial Hospital in Bolivar.

For more information please contact 417-883-7889

Email Contact

People With Congestive Heart Failure Wanted for Nationwide Research Study

Congestive heart failure is a health problem that is becoming increasingly more common.  People who suffer from CHF often experience poor quality of life and frequent hospitalizations.

This study will test an investigational drug to see if it delays events such as hospitalization related to CHF.

Candidates must be:

  • Age 18 or older
  • Currently taking medications classified as AECIs or ARBC which are commonly used to treat CHF

If you qualify and choose to participate in this medical research study you receive all study-related medical evaluations and monitoring by research professionals and study drug at no cost. Compensation for time and travel is also provided.

Clinvest is conducting this study in cooperation with Dr. John Best at Citizen’s Memorial Hospital in Bolivar.For more information please contact 417-883-7889

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Research Study for Relapsing Forms of Multiple Sclerosis
The currently available Disease Modifying Treatments (DMTs) for Relapsing Forms of Multiple Sclerosis have been shown to be only partially effective and must be administered by injection.  Clinvest, in cooperation with  neurologist Kenneth Sharlin M.D, is currently enrolling participants with relapsing forms of MS in a medical research study comparing the safety and tolerability of fingolimod, an FDA approved oral drug for relapsing forms of MS, to DMTs.
Please consider enrolling in this research study if you suffer from relapsing forms of MS and:

  • Are between the ages of 18 and 65 
  • Have been taking Extavia® (interferon β- 1b) or Betaseron®(interferon β- 1b); Avonex® (interferon β- 1a; Rebif® (interferon β- 1a); or Copaxone® (glatiramer acetate) for at least 6 months
  • Have never taken fingolimod

If you qualify and choose to participate in this research study, you will receive study drug and all study-related evaluations . Compensation for time and travel may also be provided. 

For more information please call Clinvest at 417-883-7889. Email Contact



Are Your Migraines Occurring More Frequently?
Clinvest is currently recruiting volunteers to participate in a medical research study to see if a drug that is investigational for frequent migraine plus migraine education reduces the number and severity of these headaches.
 If you:
Are age 18-65  
Have experienced a headache on 6-14 days during the past 3 months
Are willing to help find a way to prevent frequent headaches from becoming a chronic disorder

Please consider enrolling in this medical research study.  Qualified candidates will receive study related medical evaluations, investigational drug and migraine education at no charge. Compensation for time and travel is also provided. 

For more information, please contact Clinvest at 417-883-7889. Email Contact

 

Do You Suffer from the Side Effects of Daily Pain Medication?
Constipation is a common problem for those who must rely on narcotics to manage chronic pain. If you suffer from this unpleasant and uncomfortable side effect, you may be interested in participating in a medical research study testing an investigational drug used to treat opioid induced constipation.

In order to qualify you must:
> Have a diagnosed moderate to severe chronic pain condition that, for at least the last 3 months, has required around the clock pain medication.
If you meet enrollment criteria and choose to participate in this 12 week study you will receive all study-related medical evaluations and study drug at no charge. Compensation for travel is also provided.

For more information call Clinvest at 417-883-7889. Email Contact

 

Do You Suffer from Chronic Headaches?
Clinvest is currently recruiting volunteers to participate in a medical research study to see if an investigational drug reduces the number and severity of chronic headaches. If you:
> Are age 18-65
> Experience a headache on 15 or more days each month
> Are willing to help find a way to manage chronic headaches
Please consider enrolling in this medical research study.  Qualified candidates will receive study related medical evaluations and investigational drug at no charge. Compensation for time and travel is also provided. For more information, please contact Clinvest at 417-883-7889. Email Contact

Investigational Drug for Diabetic Peripheral Neuropathy
Diabetic Peripheral Neuropathy, also known as DPN, can have significant impact on the lives of Type I and II diabetics who suffer from this painful condition.
We are looking for individuals for a research study:
> Who are currently taking medications for DPN and are continue to experience pain
> Who have been diagnosed with DPN for at least 3 months
Clinvest and Dr. Melinda Crocket-Maples are currently conducting a medical research study for people who suffer from painful DPN.  The purpose of the study is to determine the safety and effectiveness of an investigational medicine in subjects with DPN.  Participants will receive either Lyrica® or placebo (an inactive look alike substance). If you qualify and choose to participate you will receive all study-related evaluations and study medication plus compensation for time and travel. 
For more information please call 417-883-7889. Email Contact

Post Herpetic Neuralgia Research Study
Post herpetic neuralgia, also known as PHN, is characterized by throbbing, stabbing or burning pain or increased sensitivity. PHN may last for months or even years after the rash associated with herpes zoster is gone.
If you:
> Have suffered from of PHN for at least 9 months
> Age between the ages of 18 and 80
You may qualify for a medical research study testing a drug that is investigational for the treatment of the pain associated with PHN. Qualified candidates will receive all study-related evaluations and study medication plus compensation for time and travel. For more information, please contact 417-883-7889. Email Contact

Have you had a mild head injury that has left you with chronic headaches?
Clinvest is conducting a medical research study testing an approved migraine drug to see if it safely and effectively relieves post traumatic headaches.
If you:
> Are between the ages of 18 and 65
> Have had a problem with headaches since the injury
> Have trouble with concentration and memory due to the headaches
Please consider volunteering for this medical research study. No insurance is necessary because if you qualify and choose to participate you will receive all study related medical evaluations and study drug at no charge.  Compensation for time and travel is also provided.For more information, please contact 883-7889.
Email Contact

Are Migraines Disrupting Your Teens Life?

Like adults, kids have migraines.  Unfortunately these headaches are often undertreated.

If your adolescent:

  • Is between the ages of 12 and 17
  • Experiences 15 or fewer days of headache each month
  • Is willing to help find treatment for adolescent migraine

Please consider their participation in this migraine research study. The purpose of the study is to test a medication already approved for adult migraine but is investigational in individuals under age 18. Study participants will receive study related medical evaluations, and study medicine at no cost to you. Compensation for time and travel is also provided.

Call 417-883-7889 for more information about your child’s possible participation in this trial.


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Find the current studies to the left. Email or call the contact to participate in a study. We look forward to working with you!

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