Onsite Research Site Map
 

Clinvest and Headache Care Center, both founded by Dr. Roger Cady, have combined research and clinical practice to offer an integrated approach to health care. Knowledge gained through research conducted by Clinvest helps to ensure that the most up-to-date treatments are available to you and your clinician.

What studies are conducted by Clinvest?

The scope of Clinvest research includes studies targeting all types of headache, and other disorders such as:  hypertension, osteoarthritis, high cholesterol, diabetes, GI disorders, asthma, low back pain, herpes, Alzheimer’s disease, and fibromyalgia. We work closely with our sponsor to continually expand our areas of study.

Our experienced staff includes certified research coordinators and in-house and satellite investigators whose specialties span the areas of neurology, internal medicine, family practice, and general clinical and neuropsychology.

 
Study Results
Click the link to see results
 
Expanding Access to Triptans
 
Milnacipran for Treatment of Fibromyalgia
 
Sumatriptan Injection
 
Combination Treatment for Menstrual Migraine and Dysmenorrhea Using
Sumatriptan–Naproxen
 
Rizatriptan 10-mg ODT for Early Treatment of Migraine and
Impact of Migraine Education on Treatment Response
 
Predictors to Adherence of Triptans
 
Botulinum Toxin Type A as Migraine Preventive. Headache. 2008;48;900-913
 

AEGIS Study:

Treatment with Axert ® at mild migraine pain
Study conducted at Clinvest 2004-2005
16 participants were from Clinvest
What is allodynia? Allodynia is a painful response to a stimulus that would not normally cause pain.  Migraine sufferers sometimes describe allodynia as: “My glasses hurt”, “It hurts to shave”, or “It hurts to comb my hair”.
 

MEWT: Migraine Early Warning Tool

Developed by Clinvest Researchers, Dennis Reeves, PhD and Kathleen Farmer, PhD

  • The MEWT was developed from ANAM*, a battery of tests designed by military scientists to measure how efficiently the brain is working.  ANAM has been used to evaluate troops for combat readiness.
  • The MEWT is programmed into handheld computers and is designed for at-home monitoring of cognitive status in migraine patients.

The MEWT and ANAM have been used in 7 studies developed by Clinvest Investigators and in cooperation with major pharmaceutical companies and the military to evaluate:

  • Prodrome (a warning that a migraine is impending)
  • Response to treatment
  • Effects of medication on brain efficiency
  • The effect of migraine on brain efficiency
  • ANAM as a reliable testing method

Farmer et al., 2003 K. Farmer, R. Cady and D. Reeves, The effects of prodrome on cognitive efficiency, Headache (2003), p. 518. a Approximately 500 Clinvest/Headache Care Center participants have been involved in these studies over the past 10 years.
Clinvest continues to develop new uses for these tools.

*Automated Neuropsychological Assessment Metrics

 
 

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